Role of locoregional therapies in the management of patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) was the sixth most common cancer and third cause of cancer-related deaths worldwide in 2020. Liver resection transplantation remain cornerstone for patients with early-stage disease represent only option potential cure HCC. However, fewer than 10% are considered suitable surgery at time diagnosis. Locoregional therapies, defined as minimally invasive image-guided liver tumour-directed procedures, integral to management This review discusses role locoregional therapies HCC emergence immune systemic treatments.